PRP Tubes Acd Tubes

Anticoagulant Citrate Dextrose Solution, nke a na-akpọkarị ACD-A ma ọ bụ Ngwọta A bụ ihe na-abụghị pyrogenic, ngwọta na-adịghị mma.A na-eji ihe a eme ihe dị ka anticoagulant na mmepụta nke platelet-rich plasma (PRP) na PRP Systems maka nhazi ọbara extracorporeal.Anticoagulants nke sitere na citrate na-eji ikike nke citrate ion chelate calcium ionized nke dị n'ime ọbara iji gbochie coagulation nke ọbara na-emepụta ihe na-abụghị ionized calcium-citrate complex.

Naanị ngwaahịa anticoagulant nke United States Food & Drug Administration kwadoro ka e jiri ya mee ihe maka nkwadebe nke PRP na usoro PRP dị iche iche bụ ACD-A.Dị ka nnyocha e mere na 2016 na PRP nwetara na anticoagulants dị iche iche na mmetụta ha na omume nke mesenchymal stromal sel na vitro na platelet ọnụ ọgụgụ, e nwere mma pụta na ojiji nke PRP maka musculoskeletal anụ ahụ.

Maka ikewapụ platelet, a na-adụ ọdụ ka dochie ọkọlọtọ sodium citrate maka Acid Citrate Dextrose (ACD-A) n'ihi na usoro ikewapụ chọrọ ọtụtụ usoro ịsa ahụ.Platelet na-akwụsi ike na 37C n'oge a na-agbagharị, mana ịtụgharị ha na ọnụ ụlọ (25 C) na-arụkwa ọrụ nke ọma.Mbelata pH site na ACD-A (ọ na-eru nso 6.5) na-enyere aka imebi mmalite nke traktị thrombin fọdụrụnụ na tubes platelet, ma na-atụnye aka n'ịkwado n'ozuzu nke morphology platelet mgbe ọ na-agbanwe ọrụ gaa na minima.Dị ka ọ na-adịkarị, ịkwesịrị iweghachite platelet na ebe nchekwa Tyrode kwesịrị ekwesị (pH 7.4) iji nwetaghachi ọrụ ha.ACD nwere ọtụtụ uru ma a bịa n'ichekwa platelet

Mgbe ejiri ACD mee ihe, nsonaazụ gosipụtara mkpụrụ platelet dị elu n'ọbara n'ozuzu ya.Otú ọ dị, iji EDTA gbakwara ume na-eto eto n'ịdị elu platelet mgbe emechara usoro centrifugation ọbara iji nweta PRP.Na-esote, iji ACD mere ka mmụba nke mkpụrụ ndụ stromal mesenchymal.Ya mere, e kwubiri na anticoagulants gụnyere ACD-A na-ekere òkè dị ukwuu na nkwadebe PRP ma nyere aka kwalite usoro ahụ ruo n'ókè dị ukwuu.